Steroids and derivatives
AdipoGen GE2270 D2
Chemical. CAS 138948-60-4. Formula C55H53N15O10S6. MW 1276.5. Isolated from Planobispora rosea. Thiopeptide antibiotic. Congener of GE2270A. Used as a starting scaffold bearing a free hydroxy group, for the production of new interesting semi-synthetic antibiotics. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens. Inhibitor of elongation factor Tu EF-Tu. Inhibits protein synthesis by blocking the GDP to GTP conformational change and by directly competing with aminoacyl-tRNA for the same binding site on EF-Tu.
eMolecules 131918-61-1 | Medchem Express | Paricalcitol | 1mg | 446271255 | HY-50919 | MFCD08067734 | 416.646 | C27H44O3
ChemScene | (R)-2-(Dimethylamino)propanoic acid | 100mg | 632323942 | CS-0158218 | 157431-09-9 | MFCD19238066 | 117.148 | C5H11NO2
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Cayman Chemical 17-EstradIol-d3 10mg
An internal standard for the quantification of 17β-estradiol by GC- or LC-MS
Medchemexpress LLC Estradiol-d4 | 66789-03-5 | 99.1% | 1 ML
Estradiol-d4 | 66789-03-5 | 99.1% | 1 ML
Selleck Chemical LLC Estradiol S1709-1g
Estradiol (17 -estradiol -Estradiol E2 17 -Oestradiol) is a human sex hormone and steroid and the primary female sex hormone Estradiol upregulates IL-6 expression through the estrogen receptor (ER ) pathway
Medchemexpress LLC Hydrocortisone hemisuccinate | 2203-97-6 | MFCD00046256 | 10 MG
Hydrocortisone hemisuccinate is a steroidal glucocorticoid research reagent used as an anti-inflammatory agent in research and analytical applications. It is supplied as solids and ready-to-use solutions for reconstitution and analytical work, and is intended for research use only (not for human consumption).
- Provides a soluble hemisuccinate ester of hydrocortisone for improved water solubility.
- Suitable as an analytical standard and research reagent.
- Available as solution formats and multiple solid quantities for flexibility in experiments.
- Contains identified molecular formula and molecular weight for analytical use.
U.S. Pharmacopeia Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Medchemexpress LLC Dexamethasone acetate | 1177-87-3 | 98.2% | 434.50 | 1 G
Dexamethasone acetate is a glucocorticoid receptor agonist that significantly reduces expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes. It is effective in controlling COVID-19 infection and inhibits inflammatory microRNA-155 exosome production in lipopolysaccharide-induced macrophage responses.
- Functions as a glucocorticoid receptor agonist.
- Decreases CD11b, CD18, and CD62L expression on neutrophils and monocytes.
- Effective in controlling COVID-19 infection.
- Inhibits inflammatory microRNA-155 exosome production in macrophage responses.
- Targets: Glucocorticoid receptor, autophagy, mitophagy, SARS-CoV, and the complement system.
- Applicable in inflammation/immunology, endocrinology, and cancer research.
Apexbio Technology LLC Prednisone 53-03-2 1g
Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
Apexbio Technology LLC Dexamethasone phosphate disodium 2392-39-4 500mg
Dexamethasone phosphate disodium (CAS 2392-39-4) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid-mediated signaling pathways thereby regulating immune and inflammatory responses Dexamethasone phosphate disodium exerts its biological activity primarily by binding to the glucocorticoid receptor initiating nuclear translocation and influencing gene transcription to suppress the expression and secretion of pro-inflammatory cytokines and chemokines Based on these pharmacological properties dexamethasone phosphate disodium holds research potential in studying inflammatory conditions immune response processes and associated signaling cascades in vitro and in vivo
Medchemexpress LLC Fluocinolone Acetonide | 500 MG
Fluocinolone is a glucocorticoid receptor agonist. It is effective in preventing both lipid accumulation and inflammation. It can also promote the proliferation of DPCs and holds a potential role in repairing injured pulp tissues.
- Glucocorticoid receptor agonist
- Effective in preventing lipid accumulation and inflammation
- Promotes the proliferation of DPCs
- Potential role in repairing injured pulp tissues
- Used to study the prevention of chemotherapy-induced peripheral neuropathy